GIGABIOME

A next generation of AMR diagnostics

AI-guided antibiotic-resistance diagnostics, personalised to the patient's microbiome — running on the PCR platforms hospitals already own.

Trained on 106,539 pathogen genomes Validated across 5,000+ whole genomes Report in under 2 hours

Antibiotic therapy fails for an overlooked reason

Resistance testing ignores the patient's microbiome — which reshapes both the bacterial community and how drugs work. The result is mistreatment, at massive human and economic cost.

1.27Mannual deaths attributable to antimicrobial resistance
43%of antibiotic prescriptions are incorrect
$300Bprojected hit to global GDP by 2050
MICROBIOME 🦠 💊 ANTIBIOTIC changes drug efficacy changes the microbiome

A resistance report in under two hours

We're building a microbiome-personalised AMR diagnostic test — currently in development — that runs on the PCR instruments hospitals already operate, and returns a susceptible / resistant call through the lab's own systems.

01

Sample

A patient sample, collected with preservative.

02

Cartridge

Multiplex PCR across a panel of resistance targets.

03

Registration

QR-linked to the patient, tracked through the workflow.

04

Report

A resistance result delivered to clinicians in under 2h.

Personalised to the patient's microbiome · validated on 5,000+ genomes · no new instruments required.

Three platforms, one diagnostic engine

Antibiotic resistance is multi-causal, so we combine genomics, microbiome science and AI into a single engine for discovering and calling resistance.

Archeion

Genomics

Calls drug resistance directly from whole-genome sequencing data.

Equilibria

Microbiome

Profiles the gut and oral microbiome and links its signatures to clinical outcomes.

Phylax

AI

A cross-species model that predicts resistance — and shows the reasoning behind every call.

Backed by peer-reviewed science

Selected journals featuring peer-reviewed work by the Gigabiome founding team.

Genomics, clinical and AI under one roof

A founding team spanning computational biology, microbiome science and world-leading clinical medicine.

FC

Dr Frederick Clasen

CEO · Co-founder

Bioinformatics and systems biology (King's College London, Francis Crick Institute).

SS

Dr Saeed Shoaie

CTO · Co-founder

Internationally recognised microbiome scientist at King's College London and founder of several biotech companies.

RJ

Prof Rajiv Jalan

CMO · Co-founder

UCL Professor of Hepatology, 500+ published articles, and founder of three clinical-stage biotech companies.

Partners & collaborators
King's College London UCL University of Cambridge Accelerate@Babraham

Let's make targeted AMR diagnosis the standard of care

For partnership, clinical collaboration or investor enquiries, we'd like to hear from you.

Email the team